ChEs/MAOs-IN-2
ChEs/MAOs-IN-2 (compound a11) is a cholinesterases and monoamine oxidases inhibitor with IC50 values of 0.10, 0.20, 0.30, 0.40 µM for MAO-A, MAO-B, AChE, and BChE, respectively. ChEs/MAOs-IN-2 has the potential for the research of Alzheimer's disease.
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- CAS No.: 693268-77-8
- Formule: C15H12N2O3S
- Masse moléculaire:300.33
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
MAO-A 0.10 μM (IC50) |
MAO-B 0.20 μM (IC50) |
AChE 0.30 μM (IC50) |
BChE 0.40 μM (IC50) |
Chemical Information
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CAS No. 693268-77-8
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Masse moléculaire 300.33
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Formule C15H12N2O3S
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SMILES
O=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=CC=C3O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)