1. Cell Cycle/DNA Damage
    Stem Cell/Wnt
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  2. ROCK
  3. Chroman 1 dihydrochloride

Chroman 1 dihydrochloride 

Cat. No.: HY-15392A
Handling Instructions

Chroman 1 dihydrochloride is a highly potent ROCK2 inhibitor, with an IC50 of 1 nM. Chroman 1 dihydrochloride also shows inhibitory activities against MRCK, with an IC50 of 150 nM.

For research use only. We do not sell to patients.

Chroman 1 dihydrochloride Chemical Structure

Chroman 1 dihydrochloride Chemical Structure

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Description

Chroman 1 dihydrochloride is a highly potent ROCK2 inhibitor, with an IC50 of 1 nM. Chroman 1 dihydrochloride also shows inhibitory activities against MRCK, with an IC50 of 150 nM[1].

IC50 & Target[1]

ROCK2

1 nM (IC50)

MRCK

150 nM (IC50)

Molecular Weight

509.43

Formula

C₂₄H₃₀Cl₂N₄O₄

SMILES

O=C([[email protected]@H]1COC2=CC=C(OC)C=C2C1)NC3=CC=C(C4=CNN=C4)C=C3OCCN(C)C.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Chroman 1Chroman1Chroman-1ROCKRho-associated protein kinaseRho-associated kinaseRho-kinaseROKrho kinaseglaucomaspinalcordinjuryInhibitorinhibitorinhibit

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Product Name:
Chroman 1 dihydrochloride
Cat. No.:
HY-15392A
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