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Referencia número: HY-111781S

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Civorebrutinib-d₄

Name: Civorebrutinib-d4
Brand: MedChemExpress
SKU: HY-111781S
Availability: PreOrder

(Synonyms: WS-413-d₄)

Civorebrutinib-d₄ (WS-413-d₄) is the deuterated-labeled Civorebrutinib (HY-111781). Civorebrutinib (WS-413) is a selective, orally active BTK and TEC inhibitor with an IC₅₀ of <100 nM for both targets. Civorebrutinib inhibits B cell activation. Civorebrutinib significantly suppresses the in vivo growth of diffuse large B-cell lymphoma cells. Civorebrutinib can be used for the research of diffuse large B-cell lymphoma.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₃H₁₈D₄ClN₇O₂
Peso molecular:467.94

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Civorebrutinib-d₄ Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
- Aplicación
Chemical Information
Pureza y Documentación
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aplicación

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 2155853-43-1
Peso molecular 467.94
Fòrmula C₂₃H₁₈D₄ClN₇O₂
SMILES

ClC(C=C1)=CN=C1OC2=C([2H])C([2H])=C(C3=NN([C@@H]4CCC5(CC5)N(C#N)C4)C(N)=C3C(N)=O)C([2H])=C2[2H]
Synonyms

WS-413-d₄
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.