COX-2-IN-23
COX-2-IN-23 (compound 9a) is a selective COX-2 inhibitor with IC50 values of 0.28 and 20.14 μM for COX-2 and COX-1. COX-2-IN-23 has anti-inflammatory activity and low ulcerogenic activity.
For research use only. We do not sell to patients.
- CAS No.: 2417995-08-3
- Formula: C24H25N5O3S2
- Molecular Weight:495.62
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
COX-2 0.28 μM (IC50) |
COX-1 20.14 μM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Mature male albino rats[1]
-
Dosage:9 mg/kg
-
Administration:Intraperitoneal injection; 0, 1, 2, 3 and 4 hours.
-
Result:Had similar ulcerogenic activity to celecoxib.
Chemical Information
-
CAS No. 2417995-08-3
-
Molecular Weight 495.62
-
Formula C24H25N5O3S2
-
SMILES
O=S(C1=CC(C(N2C3=CC=CC=C3)=NNC2=S)=CC(NCCCC)=C1OC4=CC=CC=C4)(N)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2-IN-23 Related Classifications
HY-147961 Related Classifications
Powered by Bioz