COX-2/LOX-IN-1
COX-2/LOX-IN-1 (compound 5) is a dual cyclooxygenase-2/lipoxygenase (COX-2/LOX) inhibitor with IC50s of 30 μM and 0.55 μM, for LOX and COX-2, respectively. .
For research use only. We do not sell to patients.
- Formula: C30H26N2O2
- Molecular Weight:446.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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COX-2 0.55 μM (IC50) |
LOX 30 μM (IC50) |
COX-2/LOX-IN-1 (100 μM) reveals an inhibitory activity against lipid peroxidation, the inhibitory percentage is 36%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 446.54
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Formula C30H26N2O2
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SMILES
CN(C)C(C=C1)=CC=C1/C=C/C2=CN(C=C2C(C3=CC=CC=C3)=O)C(/C=C/C4=CC=CC=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)