COX-2/NO-IN-1
COX-2/NO-IN-1 is an orally active nitric oxide synthase (iNOS), COX-2 expression and NO (IC50 of 3.52 μM) inhibitor. COX-2/NO-IN-1 has anti-inflammatory effects.
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- No. CAS: 2989882-91-7
- Fòrmula: C15H15NO3
- Peso molecular:257.28
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
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iNOS |
COX-2/NO-IN-1 (Compound 13b; 2.5-10 μM) exhibits potent activity through dose-dependent inhibiting the production of nitric oxide (NO, IC50 = 3.52 μM), TNF-α and IL-6 (84.1% and 33.6%, respectively), as well as suppressing the expression of iNOS, COX-2 and TLR4 proteins in LPS-stimulated RAW264.7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2989882-91-7
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Peso molecular 257.28
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Fòrmula C15H15NO3
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SMILES
C=C(C(C1=CC2=CC=CC=C2N=C1)O)C(OCC)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2/NO-IN-1 Related Classifications
HY-146161 Related Classifications
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