CP-85958
CP-85958 is a specific leukotriene D4 (LTD4) receptor antagonist. CP-85958 can be used in the research of inflammatory diseases such as asthma.
For research use only. We do not sell to patients.
- CAS No.: 134002-60-1
- Formula: C25H20FNO5S
- Molecular Weight:465.49
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Leukotriene Receptor Isoforms
More
Biological Activity
|
LTD4 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
8.1 μM
Compound: 5 ((+)-CP-85958)
|
Inhibition of 5-Lipoxygenase (5-LO) in rat basophilic leukemia cells
Inhibition of 5-Lipoxygenase (5-LO) in rat basophilic leukemia cells
|
10.1016/0960-894X(95)00225-I |
| U-937 | IC50 |
0.31 μM
Compound: 3
|
Compound was evaluated for influx of calcium mobilization in human U937 cells
Compound was evaluated for influx of calcium mobilization in human U937 cells
|
[PMID: 9873435] |
| U-937 | IC50 |
0.31 μM
Compound: 3
|
Compound was tested for its ability to inhibit calcium influx in human U937 cells
Compound was tested for its ability to inhibit calcium influx in human U937 cells
|
[PMID: 9934474] |
Chemical Information
-
CAS No. 134002-60-1
-
Molecular Weight 465.49
-
Formula C25H20FNO5S
-
SMILES
O=C(O)C1=CC=CC(C[C@@H]2COC3=CC=C(OCC4=NC5=CC(F)=CC=C5S4)C=C3[C@@H]2O)=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CP-85958 Related Classifications
HY-19241 Related Classifications
Powered by Bioz