2. GPCR/G Protein
  3. Leukotriene Receptor
  4. CP-85958

CP-85958 is a specific leukotriene D4 (LTD4) receptor antagonist. CP-85958 can be used in the research of inflammatory diseases such as asthma.

For research use only. We do not sell to patients.

CP-85958

CP-85958 Chemical Structure

CAS No. : 134002-60-1

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

CP-85958 Related Antibodies

Top Publications Citing Use of Products

View All Leukotriene Receptor Isoform Specific Products:

View All Isoforms
LTB4 LTC4/CysLT2 LTD4/CysLT1 LTE4

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

CP-85958 is a specific leukotriene D4 (LTD4) receptor antagonist. CP-85958 can be used in the research of inflammatory diseases such as asthma[1].

IC50 & Target[1]

LTD4

 

Cellular Effect
Cell Line Type Value Description References
RBL-1 IC50
8.1 μM
Compound: 5 ((+)-CP-85958)
Inhibition of 5-Lipoxygenase (5-LO) in rat basophilic leukemia cells
Inhibition of 5-Lipoxygenase (5-LO) in rat basophilic leukemia cells
10.1016/0960-894X(95)00225-I
U-937 IC50
0.31 μM
Compound: 3
Compound was evaluated for influx of calcium mobilization in human U937 cells
Compound was evaluated for influx of calcium mobilization in human U937 cells
[PMID: 9873435]
U-937 IC50
0.31 μM
Compound: 3
Compound was tested for its ability to inhibit calcium influx in human U937 cells
Compound was tested for its ability to inhibit calcium influx in human U937 cells
[PMID: 9934474]
Molecular Weight

465.49

Formula

C25H20FNO5S
CAS No.
SMILES

O=C(O)C1=CC=CC(C[C@@H]2COC3=CC=C(OCC4=NC5=CC(F)=CC=C5S4)C=C3[C@@H]2O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

CP-85958 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CP-85958134002-60-1CP85958CP 85958Leukotriene ReceptorLTD4asthmaInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
CP-85958
Cat. No.:
HY-19241
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.