CRBN ligand-111
CRBN ligand-111 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.
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- CAS. Nr.: 3036607-67-4
- Formel: C12H8BrClN2O2
- Molecular Weight:327.56
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3036607-67-4
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Molecular Weight 327.56
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Formel C12H8BrClN2O2
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SMILES
N#CC1=C(Br)C=CC(C(CC2)C(NC2=O)=O)=C1Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)