CRBN ligand-148
Based on 1 Customer Validation
CRBN ligand-148 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 3036607-19-6
- Formula: C11H8BrCl2NO2
- Molecular Weight:337.00
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3036607-19-6
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Appearance Solid
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Molecular Weight 337.00
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Formula C11H8BrCl2NO2
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Color White to off-white
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SMILES
O=C(C(C1=C(Cl)C=C(Br)C=C1Cl)CC2)NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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