CRBN ligand-404
CRBN ligand-404 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-404 can be linked to a target protein ligand via a linker to form a PROTAC.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C₁₂H₉FN₂O₂
- Peso molecular:232.21
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
|
Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
-
Peso molecular 232.21
-
Fòrmula C₁₂H₉FN₂O₂
-
SMILES
C#CC1C=C(C=CC=1F)N2C(=O)NC(=O)CC2
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)