CRBN ligand-412
CRBN ligand-412 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-412 can be linked to a target protein ligand via a linker to form a PROTAC.
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- CAS. Nr.: 2736511-31-0
- Formel: C17H22N2O3
- Molecular Weight:302.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2736511-31-0
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Molecular Weight 302.37
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Formel C17H22N2O3
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SMILES
O=C1NC(=O)C(C2=CC=C(C=C2)N3CCC(CO)CC3)CC1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CRBN ligand-412 Related Classifications
HY-W998291 Related Classifications
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