2. Metabolic Enzyme/Protease Others
  3. Carboxylesterase (CES) Fluorescent Dye
  4. CycLuc1 methyl ester

CycLuc1 methyl ester (Example 1) is a selective CES1 substrate and indirect bioluminescent inducer. CycLuc1 methyl ester undergoes catalytic hydrolysis via CES1-mediated ester bond cleavage to form a carboxyl product. The carboxyl product of CycLuc1 methyl ester undergoes an oxidation reaction with luciferase to generate a detectable bioluminescent signal. CycLuc1 methyl ester enables quantitative detection of CES1 activity.

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CycLuc1 methyl ester

CycLuc1 methyl ester Chemical Structure

CAS No. : 2770784-56-8

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CycLuc1 methyl ester Related Antibodies

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Description

CycLuc1 methyl ester (Example 1) is a selective CES1 substrate and indirect bioluminescent inducer. CycLuc1 methyl ester undergoes catalytic hydrolysis via CES1-mediated ester bond cleavage to form a carboxyl product. The carboxyl product of CycLuc1 methyl ester undergoes an oxidation reaction with luciferase to generate a detectable bioluminescent signal. CycLuc1 methyl ester enables quantitative detection of CES1 activity[1].

IC50 & Target[1]

CES1

 

Molecular Weight

319.40

Formula

C14H13N3O2S2
CAS No.
SMILES

O=C(OC)[C@H]1CSC(C(S2)=NC3=C2C=C4NCCC4=C3)=N1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CycLuc1 methyl ester Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CycLuc1 methyl ester2770784-56-8Carboxylesterase (CES)Fluorescent DyeCarboxylesteraseCarboxylic-ester Hydrolasehuman liver microsomeshuman carboxylesterase 1luciferase-transfected miceCES1HCT116 cellsHepG2 cellsluciferase-transfected cellsU87 cellsexperimental animalsluciferaseInhibitorinhibitorinhibit

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CycLuc1 methyl ester
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HY-D3461
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