D-Alanine-13C3
D-Alanine-13C3 ((R)-Alanine-13C3) is the 13C-labeled D-Alanine (HY-41700). D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
For research use only. We do not sell to patients.
- CAS No.: 286460-72-8
- Formula: 13C3H7NO2
- Molecular Weight:92.07
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 286460-72-8
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Unlabeled Cas 338-69-2
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Molecular Weight 92.07
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Formula 13C3H7NO2
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SMILES
N[13C@H]([13CH3])[13C](O)=O
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Synonyms
(R)-Alanine-13C3; Ba 2776-13C3; D-α-Alanine-13C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Schmieden V, et al. Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol Pharmacol. 1995 Nov;48(5):919-27. [Content Brief]
[2]. Saitoh T, et al. A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br J Pharmacol. 1994 Sep;113(1):165-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)