D-Mannose-13C-5
Based on 1 Customer Validation
D-Mannose-13C-5 is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote.
For research use only. We do not sell to patients.
- Purity: 99.83%
- CAS No.: 115973-81-4
- Formula: C513CH12O6
- Molecular Weight:181.15
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 115973-81-4
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Unlabeled Cas 3458-28-4
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Appearance Solid
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Molecular Weight 181.15
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Formula C513CH12O6
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Color White to off-white
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SMILES
O=C[C@H]([C@H]([C@@H]([C@@H]([13CH2]O)O)O)O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
H2O : 100 mg/mL (552.03 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Genovese C, et al. Effects of a new combination of plant extracts plus d-mannose for the management of uncomplicated recurrent urinary tract infections. J Chemother. 2018 Apr;30(2):107-114. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.5203 mL | 27.6014 mL | 55.2029 mL | 138.0072 mL |
| 5 mM | 1.1041 mL | 5.5203 mL | 11.0406 mL | 27.6014 mL | |
| 10 mM | 0.5520 mL | 2.7601 mL | 5.5203 mL | 13.8007 mL | |
| 15 mM | 0.3680 mL | 1.8401 mL | 3.6802 mL | 9.2005 mL | |
| 20 mM | 0.2760 mL | 1.3801 mL | 2.7601 mL | 6.9004 mL | |
| 25 mM | 0.2208 mL | 1.1041 mL | 2.2081 mL | 5.5203 mL | |
| 30 mM | 0.1840 mL | 0.9200 mL | 1.8401 mL | 4.6002 mL | |
| 40 mM | 0.1380 mL | 0.6900 mL | 1.3801 mL | 3.4502 mL | |
| 50 mM | 0.1104 mL | 0.5520 mL | 1.1041 mL | 2.7601 mL | |
| 60 mM | 0.0920 mL | 0.4600 mL | 0.9200 mL | 2.3001 mL | |
| 80 mM | 0.0690 mL | 0.3450 mL | 0.6900 mL | 1.7251 mL | |
| 100 mM | 0.0552 mL | 0.2760 mL | 0.5520 mL | 1.3801 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.