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Art. -Nr.: HY-165309

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UK-390957

UK-390957 is a sulfonamide. UK-390957 binds to phosphatidylserine and carbonic anhydrase. UK-390957 can be used in the research of premature ejaculation.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 364321-71-1
Formel: C₁₆H₂₀N₂O₃S₂
Molecular Weight:352.47

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

UK-390957 Chemical Structure

CAS. Nr.: 364321-71-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

UK-390957 is a sulfonamide. UK-390957 binds to phosphatidylserine and carbonic anhydrase. UK-390957 can be used in the research of premature ejaculation^[1].

Alle Carbonic Anhydrase Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	4 nM Compound: 20	Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells	[PMID: 18782666]

Chemical Information

CAS. Nr. 364321-71-1
Molecular Weight 352.47
Formel C₁₆H₂₀N₂O₃S₂
SMILES

O=S(C1=CC=C(OC2=CC=C(SC)C=C2)C(CN(C)C)=C1)(N)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Andrews M D, et al. The Discovery of UK-390957: the Challenge of Targeting a Short Half-life, Rapid Tmax SSRI. 2010.

[2]. Small H, et al. Measurement of binding of basic drugs to acidic phospholipids using surface plasmon resonance and incorporation of the data into mechanistic tissue composition equations to predict steady-state volume of distribution. Drug Metab Dispos. 2011 Oct;39(10):1789-93. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
Chemical Information
Reinheit & Dokumentation
Verweise

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UK-390957

Alle Carbonic Anhydrase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

UK-390957 Related Classifications

HY-165309 Related Classifications