A-78773
A-78773 is a 5-lipoxygenase inhibitor. A-78773 can inhibit the formation of LTB4 in human whole blood and human neutrophils, with IC50 values of 85 nM and 20 nM, respectively. A-78773 can be used in the study of inflammation-related diseases.
For research use only. We do not sell to patients.
- CAS No.: 141579-67-1
- Formula: C15H13FN2O4
- Molecular Weight:304.27
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-2H3 | IC50 |
298 nM
Compound: A-78773
|
Inhibition of 5-lipoxygenase mediated conversion of [14C]arachidonic acid to leukotrienes in RBL-2H3 cells
Inhibition of 5-lipoxygenase mediated conversion of [14C]arachidonic acid to leukotrienes in RBL-2H3 cells
|
[PMID: 9599246] |
Chemical Information
-
CAS No. 141579-67-1
-
Molecular Weight 304.27
-
Formula C15H13FN2O4
-
SMILES
O=C(N(O)C(C#CC1=CC=C(O1)OC2=CC=C(C=C2)F)C)N
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A-78773 Related Classifications
HY-120606 Related Classifications
Powered by Bioz