Anticancer agent 301
Anticancer agent 301 is an anticancer agent. Anticancer agent 301 selectively downregulates the phosphorylation level of ERK1/2 without affecting the NF-κB p65 subunit. Anticancer agent 301 exhibits antiproliferative activity against breast cancer cells and can be used in breast cancer-related research.
For research use only. We do not sell to patients.
- Formula: C20H18N2O2
- Molecular Weight:318.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ERK1 |
ERK2 |
Anticancer agent 301 potently inhibits proliferation of MCF-7 human breast cancer cells with an IC50 of 15.34 ± 0.17 μM[1].
Anticancer agent 301 (12.5-100 μM) selectively inhibits ERK1/2 phosphorylation in MCF-7 human breast cancer cells at 25 μM, without affecting NF-κB p65 phosphorylation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 318.37
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Formula C20H18N2O2
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SMILES
O=C(N1CCC2=C(NC3=CC=CC=C32)C1)/C=C/C4=CC=C(C=C4)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 301 Related Classifications
HY-181232 Related Classifications
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