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D-(+)-Trehalose

(Synonyms: D-Trehalose; α,α-Trehalose)
9 Cited Publications
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Based on 9 publication(s) in Google Scholar

D-(+)-Trehalose (α,α-Trehalose) is an orally active disaccharide, showing anti-desiccant and cryopreservative activities. D-(+)-Trehalose acts as an osmolyte, and stress protectant and helps in the storage and transport of carbon. D-(+)-Trehalose can be used as a food ingredient and pharmaceutical excipient.

For research use only. We do not sell to patients.

  • Purity: 99.94%
  • CAS No.: 99-20-7
  • Formula: C12H22O11
  • Molecular Weight:342.30
  • Storage:

    4°C, stored under nitrogen

    * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

  • D-(+)-Trehalose Chemical Structure
    D-(+)-Trehalose Chemical Structure
  • Experimental Validation Results for D-(+)-Trehalose
  • Experimental Validation Results for D-(+)-Trehalose
  • Experimental Validation Results for D-(+)-Trehalose
  • Experimental Validation Results for D-(+)-Trehalose
  • Experimental Validation Results for D-(+)-Trehalose
  • Experimental Validation Results for D-(+)-Trehalose
CAS No.: 99-20-7
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  • D-(+)-Trehalose Chemical Structure
    D-(+)-Trehalose Chemical Structure
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    D-(+)-Trehalose purchased from MedChemExpress. Usage Cited in: Res Sq. 2025 Jul 13.

    Customer Validation
     D-(+)-Trehalose (trehalose) (50 mM; 24 h). Secondary screen cell-based assay for p62 expression. Dot plot representation of the effects of the 17 compounds on p62 expression after 24 hours of treatment and cell viability. Quantification of total p62 puncta area following treatment relative to the control DMSO 0.1%, using HCS Studio software. Each bar represents the mean ± SD (n=3).

  • 1/16

    D-(+)-Trehalose purchased from MedChemExpress. Usage Cited in: Res Sq. 2025 Jul 13.

    Customer Validation
     D-(+)-Trehalose (trehalose) (50 mM; 24 h). Cell-based screen for drug efficacy on membrane repair phenotype. Measurement of cell mortality after hypo-osmotic shock on DYSFS1173X immortalized myoblasts pretreated for 24 hours with the 17 compounds. Each point represents the mean ± SD (n=4) of a representative experiment from three independent experiments.

  • 1/16

    D-(+)-Trehalose purchased from MedChemExpress. Usage Cited in: Ren Fail. 2024 Dec;46(1):2338933. [Abstract]

    Customer Validation
     D-(+)-Trehalose (Tre) (50 mM; 2 h). The expression of cytoplasmic TFEB and nuclear TFEB was analyzed by western blotting.

  • 1/16

    D-(+)-Trehalose purchased from MedChemExpress. Usage Cited in: Ren Fail. 2024 Dec;46(1):2338933. [Abstract]

    Customer Validation
     D-(+)-Trehalose (Tre) (50 mM; 2 h). Autophagic vacuoles in HK-2 cells were observed by the transmission electron microscope, and yellow arrows represented autophagic vacuoles (×4,000, or ×30,000).

  • 1/16

    D-(+)-Trehalose purchased from MedChemExpress. Usage Cited in: Ren Fail. 2024 Dec;46(1):2338933. [Abstract]

    Customer Validation
     D-(+)-Trehalose (Tre) (50 mM; 2 h). The mRNA levels of fibronectin, collagen I, α-SMA and E-cadherin were assessed by RT-qPCR.

  • 1/16

    D-(+)-Trehalose purchased from MedChemExpress. Usage Cited in: Ren Fail. 2024 Dec;46(1):2338933. [Abstract]

    Customer Validation
     D-(+)-Trehalose (Tre) (50 mM; 2 h). E-cadherin and α-SMA was detected by immunoinfluorence staining (Bar = 25 μm).

  • D-(+)-Trehalose