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Cat. No.: HY-120627

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BMS-442606

BMS-442606, the S-enantiomer of 6-hydroxybuspirone (6OHB), is an orally active 5-HT_1A partial agonist. BMS-442606 can be used for generalized anxiety disorder (GAD) research.

For research use only. We do not sell to patients.

CAS No.: 477930-31-7
Formula: C₂₁H₃₁N₅O₃
Molecular Weight:401.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

BMS-442606 Chemical Structure

CAS No.: 477930-31-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

BMS-442606, the S-enantiomer of 6-hydroxybuspirone (6OHB), is an orally active 5-HT_1A partial agonist. BMS-442606 can be used for generalized anxiety disorder (GAD) research^[1].

IC₅₀ & Target^[1]

5-HT_1A Receptor

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 477930-31-7
Molecular Weight 401.50
Formula C₂₁H₃₁N₅O₃
SMILES

O=C(N(CCCCN1CCN(C2=NC=CC=N2)CC1)C(C3)=O)[C@@H](O)C43CCCC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dockens RC, et al. Pharmacokinetics of 6-hydroxybuspirone and its enantiomers administered individually or following buspirone administration in humans. Biopharm Drug Dispos. 2007 Oct;28(7):393-402. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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BMS-442606

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BMS-442606 Related Classifications

HY-120627 Related Classifications