NBD-10007
NBD-10007 is a CD4 agonist. NBD-10007 has anti-HIV-1 viral activity.
For research use only. We do not sell to patients.
- CAS No.: 1375736-65-4
- Formula: C20H25ClN4O3S
- Molecular Weight:436.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT2 | CC50 |
>62 μM
Compound: 9, NBD-10007, diastereoisomeric mixture
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Cytotoxicity against human MT2 cells after 4 days by XTT assay
Cytotoxicity against human MT2 cells after 4 days by XTT assay
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[PMID: 22524483] |
| MT2 | IC50 |
4.2 μM
Compound: 9, NBD-10007, diastereoisomeric mixture
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Inhibition of X4-tropic HIV1 3B gp120-mediated entry into human MT2 cells assessed as Inhibition of p24 production incubated overnight followed by compound wash-out measured after 4 days post-infection by multi-cycle neutralization assay
Inhibition of X4-tropic HIV1 3B gp120-mediated entry into human MT2 cells assessed as Inhibition of p24 production incubated overnight followed by compound wash-out measured after 4 days post-infection by multi-cycle neutralization assay
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[PMID: 22524483] |
Chemical Information
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CAS No. 1375736-65-4
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Molecular Weight 436.96
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Formula C20H25ClN4O3S
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SMILES
O=C(C(NC(C1NCCCC1)C2=NC(C)=C(CCO)S2)=O)NC3=CC=C(C=C3)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NBD-10007 Related Classifications
HY-123756 Related Classifications
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