Polymyxin D1
Polymyxin D1 is a heteropeptide antibiotic found in different strains of Bacillus polymyxa, and its effect against Gram-negative bacteria is greater than that against Gram-positive bacteria.
For research use only. We do not sell to patients.
- CAS No.: 10072-50-1
- Formula: C50H93N15O15
- Molecular Weight:1144.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 10072-50-1
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Molecular Weight 1144.36
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Formula C50H93N15O15
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SMILES
CC[C@@H](CCCCC(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H]1CCNC([C@H]([C@H](O)C)NC([C@H](CCN)NC([C@H](CCN)NC([C@H]([C@H](O)C)NC([C@@H](CC(C)C)NC([C@H](CCN)NC1=O)=O)=O)=O)=O)=O)=O)=O)CO)=O)[C@H](O)C)=O)CCN)=O)C
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Sequence
(S)-6-Methyloctanoic acid-Dab-Thr-DSer-cyclo(Dab-Dab-DLeu-Thr-Dab-Dab-Thr)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Polymyxin D1 Related Classifications
HY-N15115 Related Classifications
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