DNMT2-IN-1
DNMT2-IN-1 (compound 80) is a potent and selective DNMT2 (DNA methyltransferase 2) inhibitor with an IC50 value of 1.2 μM, and has the potential for mental and metabolic disorders or cancer research.
For research use only. We do not sell to patients.
- Formula: C20H23BrN8O9S.3/2C2HF3O2
- Molecular Weight:803.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA Methyltransferase Isoforms
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Biological Activity
DNA methyltransferase 2 (DNMT2) [1] IC50:1.2 μM (DNA methyltransferase 2,DNMT2)[1]
DNMT2-IN-1 (compound 80) (100 μM) inhibits hDNMT2 with inhibitory rate of 98.7%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 803.45
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Formula C20H23BrN8O9S.3/2C2HF3O2
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SMILES
N[C@H](C(O)=O)CCN(S(=O)(C1=CC([N+]([O-])=O)=C(Br)C=C1)=O)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=C(N=C3)C(N)=NC=N4)O)O.O=C(O)C(F)(F)F.[3/2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)