1. Cell Cycle/DNA Damage
  2. DNA Alkylator/Crosslinker
  3. Duocarmycin

Duocarmycin 

Cat. No.: HY-128915
Handling Instructions

Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) .

For research use only. We do not sell to patients.

Duocarmycin Chemical Structure

Duocarmycin Chemical Structure

CAS No. : 1116745-06-2

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Description

Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) [1].

Molecular Weight

463.96

Formula

C₂₆H₂₆ClN₃O₃

CAS No.

1116745-06-2

SMILES

O=C(N1C[[email protected]@H](CCl)C2=C1C=C(O)C3=CC=CC=C23)C(N4)=CC5=C4C=CC(OCCN(C)C)=C5

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Duocarmycin
Cat. No.:
HY-128915
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