1. Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
    Anti-infection
  2. Reactive Oxygen Species
    Virus Protease
  3. (E)-3,4-Dimethoxycinnamic acid

(E)-3,4-Dimethoxycinnamic acid (Synonyms: (E)-O-Methylferulic acid)

Cat. No.: HY-N1778A
Handling Instructions

(E)-3,4-Dimethoxycinnamic acid is the less active isomer of 3,4-Dimethoxycinnamic acid. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway. Anti-apoptotic effects.

For research use only. We do not sell to patients.

(E)-3,4-Dimethoxycinnamic acid Chemical Structure

(E)-3,4-Dimethoxycinnamic acid Chemical Structure

CAS No. : 14737-89-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

(E)-3,4-Dimethoxycinnamic acid is the less active isomer of 3,4-Dimethoxycinnamic acid. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway[1]. Anti-apoptotic effects[1].

In Vitro

3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 µM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells[1].
3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) inhibits the expression levels of Nox4 and p22phox in L-02 cells[1].
3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells[1].
3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

208.21

Formula

C₁₁H₁₂O₄

CAS No.
SMILES

O=C(/C=C/C1=CC=C(C(OC)=C1)OC)O.[(E)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
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Keywords:

(E)-3,4-Dimethoxycinnamic acid(E)-O-Methylferulic acidReactive Oxygen SpeciesVirus ProteaseInhibitorinhibitorinhibit

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(E)-3,4-Dimethoxycinnamic acid
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HY-N1778A
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