(E)-Dehydrodiconiferyl alcohol
(E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors. And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area.
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- CAS. Nr.: 528814-97-3
- Formel: C20H22O6
- Molecular Weight:358.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hep 3B2 | IC50 |
65.5 μM
Compound: 2
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Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay
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[PMID: 29567344] |
| HepG2 | IC50 |
78.6 μM
Compound: 2
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Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
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[PMID: 29567344] |
Chemical Information
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CAS. Nr. 528814-97-3
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Molecular Weight 358.39
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Formel C20H22O6
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SMILES
OCC1C2=CC(/C=C/CO)=CC(OC)=C2OC1C3=CC(OC)=C(C=C3)O.[(E)]
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Structure Classification
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Costa G, et al. In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with IX and XII hCA Inhibition. Antioxidants (Basel). 2020;9(9):775. Published 2020 Aug 21. [Content Brief]
[2]. Hu X, et al. Dehydrodiconiferyl alcohol from Silybum marianum (L.) Gaertn accelerates wound healing via inactivating NF-κB pathways in macrophages. J Pharm Pharmacol. 2020;72(2):305-317. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(E)-Dehydrodiconiferyl alcohol Related Classifications
HY-N2682A Related Classifications
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