(E)-Dehydrodiconiferyl alcohol

Cat. No.: HY-N2682A: Data Sheet Handling Instructions
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(E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors. And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area.

For research use only. We do not sell to patients.

(E)-Dehydrodiconiferyl alcohol Chemical Structure

CAS No. : 528814-97-3

Size	Stock
5 mg	Get quote	Estimated Time of Arrival: December 31
10 mg	Get quote	Estimated Time of Arrival: December 31
25 mg	Get quote	Estimated Time of Arrival: December 31

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This product is a controlled substance and not for sale in your territory.

Other Forms of (E)-Dehydrodiconiferyl alcohol:

Dehydrodiconiferyl alcohol In-stock
(7R,8S)-Dehydrodiconiferyl alcohol Get quote

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•Related Small Molecules:

•Related Proteins:

View All Carbonic Anhydrase Isoform Specific Products:

View All Isoforms

CA CA I CA Ⅱ CA IX CA XII CA VII CA VI CA VA CA VB CA XIII CA XIV

Biological Activity
Purity & Documentation
References
Customer Review

Description

(E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors^[1]. And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
Hep 3B2	IC₅₀	65.5 μM Compound: 2	Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29567344]
HepG2	IC₅₀	78.6 μM Compound: 2	Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29567344]

Molecular Weight

358.39

Formula

C₂₀H₂₂O₆

CAS No.

528814-97-3

SMILES

OCC1C2=CC(/C=C/CO)=CC(OC)=C2OC1C3=CC(OC)=C(C=C3)O.[(E)]

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Costa G, et al. In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with IX and XII hCA Inhibition. Antioxidants (Basel). 2020;9(9):775. Published 2020 Aug 21. [Content Brief]

[2]. Hu X, et al. Dehydrodiconiferyl alcohol from Silybum marianum (L.) Gaertn accelerates wound healing via inactivating NF-κB pathways in macrophages. J Pharm Pharmacol. 2020;72(2):305-317. [Content Brief]