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Cat. No.: HY-N2682A

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(E)-Dehydrodiconiferyl alcohol

(E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors. And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area.

For research use only. We do not sell to patients.

CAS No.: 528814-97-3
Formula: C₂₀H₂₂O₆
Molecular Weight:358.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

(E)-Dehydrodiconiferyl alcohol Chemical Structure

CAS No.: 528814-97-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

(E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors^[1]. And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area^[2].

All Carbonic Anhydrase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Hep 3B2	IC₅₀	65.5 μM Compound: 2	Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29567344]
HepG2	IC₅₀	78.6 μM Compound: 2	Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29567344]

Chemical Information

CAS No. 528814-97-3
Molecular Weight 358.39
Formula C₂₀H₂₂O₆
SMILES

OCC1C2=CC(/C=C/CO)=CC(OC)=C2OC1C3=CC(OC)=C(C=C3)O.[(E)]
Structure Classification
- Phenylpropanoids
- Lignans
- Phenols
- Monophenols
Initial Source
- Plants
- Compositae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Costa G, et al. In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with IX and XII hCA Inhibition. Antioxidants (Basel). 2020;9(9):775. Published 2020 Aug 21. [Content Brief]

[2]. Hu X, et al. Dehydrodiconiferyl alcohol from Silybum marianum (L.) Gaertn accelerates wound healing via inactivating NF-κB pathways in macrophages. J Pharm Pharmacol. 2020;72(2):305-317. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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References

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(E)-Dehydrodiconiferyl alcohol

All Carbonic Anhydrase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(E)-Dehydrodiconiferyl alcohol Related Classifications

HY-N2682A Related Classifications