EGFR/COX-2-IN-2
EGFR/COX-2-IN-2 (Compound 10a) is a dual inhibitor targeting epidermal growth factor receptor (EGFR) (IC50= 6.0 μM) and cyclooxygenase-2 (COX-2) (IC50=50 μM). EGFR/COX-2-IN-2 induces S-phase cell cycle arrest and apoptosis. EGFR/COX-2-IN-2 is promising for research of cancers and inflammation-related diseases.
For research use only. We do not sell to patients.
- Formula: C23H20N4O3S
- Molecular Weight:432.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Biological Activity
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COX-2 50 μM (IC50) |
Chemical Information
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Molecular Weight 432.49
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Formula C23H20N4O3S
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SMILES
O=C(NCC1=CC=CC=C1)C(C=C2C3=CC=CC=C3)=NN2C(C=C4)=CC=C4S(=O)(N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR/COX-2-IN-2 Related Classifications
HY-178440 Related Classifications
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