EGFR-IN-15
Based on 1 Customer Validation
EGFR-IN-15 (compound I-005) is a EGFR inhibitor with an IC50 of 4 nM. EGFR-IN-15 can be used for oncological diseases research.
For research use only. We do not sell to patients.
- Purity: 96.21%
- CAS No.: 2573869-16-4
- Formula: C24H25BrN6O2
- Molecular Weight:509.40
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All EGFR Isoforms
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Biological Activity
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EGFR 4 nM (IC50) |
Chemical Information
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CAS No. 2573869-16-4
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Appearance Solid
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Molecular Weight 509.40
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Formula C24H25BrN6O2
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Color White to off-white
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SMILES
C[C@H]1CN2C3=CC(Br)=CC=C3N/C2=N\C(C4=CC(C)=NC(C5=C(N(N=C5)C)OCCC1)=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (196.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9631 mL | 9.8155 mL | 19.6309 mL | 49.0773 mL |
| 5 mM | 0.3926 mL | 1.9631 mL | 3.9262 mL | 9.8155 mL | |
| 10 mM | 0.1963 mL | 0.9815 mL | 1.9631 mL | 4.9077 mL | |
| 15 mM | 0.1309 mL | 0.6544 mL | 1.3087 mL | 3.2718 mL | |
| 20 mM | 0.0982 mL | 0.4908 mL | 0.9815 mL | 2.4539 mL | |
| 25 mM | 0.0785 mL | 0.3926 mL | 0.7852 mL | 1.9631 mL | |
| 30 mM | 0.0654 mL | 0.3272 mL | 0.6544 mL | 1.6359 mL | |
| 40 mM | 0.0491 mL | 0.2454 mL | 0.4908 mL | 1.2269 mL | |
| 50 mM | 0.0393 mL | 0.1963 mL | 0.3926 mL | 0.9815 mL | |
| 60 mM | 0.0327 mL | 0.1636 mL | 0.3272 mL | 0.8180 mL | |
| 80 mM | 0.0245 mL | 0.1227 mL | 0.2454 mL | 0.6135 mL | |
| 100 mM | 0.0196 mL | 0.0982 mL | 0.1963 mL | 0.4908 mL |