EGFR-IN-158
EGFR-IN-158 (compound 12e) is an orally active EGFR inhibitor with an IC50 of 0.22 nM for EGFR(Del19/T790M). EGFR-IN-158 inhibits phosphorylation and downstream signaling by binding to EGFR, thereby inhibiting the proliferation of tumor cell lines and promoting apoptosis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C27H35ClN8O4S
- Peso molecular:603.14
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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Peso molecular 603.14
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Fòrmula C27H35ClN8O4S
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SMILES
C=CC(NC1=CC(NC2=NC=C(Cl)C(NC3=CC=CC=C3S(=O)(NCC)=O)=N2)=C(OC)C=C1N(CCN(C)C)C)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)