EGFR-IN-163
EGFR-IN-163 (Compound 13) is a competitive epidermal growth factor receptor (EGFR) inhibitor (IC50=0.079 μM, selective for HER-2 inhibition). EGFR-IN-163 induces tumor cell apoptosis and cell cycle arrest at G₂/M phase. EGFR-IN-163 is promising for research of estrogen receptor-positive (ER+) breast cancer.
For research use only. We do not sell to patients.
- Formula: C39H49N7O4
- Molecular Weight:679.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
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HER2 |
Chemical Information
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Molecular Weight 679.85
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Formula C39H49N7O4
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SMILES
COC(C1=CC(C2=CN(C3=CC=C(OCCCCCCCC)C=C3)N=N2)=NC(C4=CN(C5=CC=C(OCCCCCCCC)C=C5)N=N4)=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)