EGFR-IN-164
EGFR-IN-164 (Compound 4) is a selective and covalent allosteric EGFR inhibitor. EGFR-IN-164 significantly inhibits the activity of EGFRL858R/T790M/C797S kinase (IC50: 48.1 nM) and proliferation of of EGFR-mutant cells. EGFR-IN-164 can be used for drug resistance of cancer research.
For research use only. We do not sell to patients.
- Formula: C23H21FN4O3S2
- Molecular Weight:484.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 484.57
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Formula C23H21FN4O3S2
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SMILES
C=CS(=O)(C=C)=NC1=CC=CC2=C1CN(C2)C(C3=CC(F)=CC=C3O)C(NC4=NC=CS4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)