EGFR-IN-179
EGFR-IN-179 (Compound 8d) is an EGFR inhibitor (IC50: 0.068 μM for EGFR L858R/T790M/C797S; 2.56 μM for EGFR-WT-TK). EGFR-IN-179 has anticancer activity against non-small cell lung cancer.
For research use only. We do not sell to patients.
- CAS No.: 3078678-28-8
- Formula: C23H18N4O4S
- Molecular Weight:446.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
IC50: 0.068 μM for EGFR L858R/T790M/C797S; 2.56 μM for EGFR-WT-TK[1]
Chemical Information
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CAS No. 3078678-28-8
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Molecular Weight 446.48
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Formula C23H18N4O4S
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SMILES
OS(C(C(C=CC=C1)=C1C=C2)=C2NC3=NC(NCC4=CC=CO4)=C(C=CC=C5)C5=N3)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)