EGFR-IN-184
EGFR-IN-184 (compound 5p) is an EGFR inhibitor (IC50 = 65.6 nM). EGFR-IN-184 has anti proliferative activity against various tumor cells, such as T47D (IC50 = 15 μM), PC3 (IC50 = 55 μM), HCT116 (IC50 = 36 μM) cells. EGFR-IN-184 can significantly induce cell apoptosis and block the cell cycle. EGFR-IN-184 can be used for research on various types of cancer.
For research use only. We do not sell to patients.
- Formula: C20H16ClN5O3S
- Molecular Weight:441.89
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
More
Biological Activity
Chemical Information
-
Molecular Weight 441.89
-
Formula C20H16ClN5O3S
-
SMILES
CC1=CC2=C(N=C(S2)NC(CN3C=C(N=N3)COC(C4=CC=C(C=C4)Cl)=O)=O)C=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)