EGFR-IN-30
EGFR-IN-30 is a potent EGFR inhibitor with IC50s of 1-10 nM, <1 nM for EGFR (WT), EGFR (L858R/T790M/C797S), respectively. EGFR-IN-30 has potential for cell proliferative diseases, such as cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2726463-68-7
- Formula: C28H33BrN7O2P
- Molecular Weight:610.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All EGFR Isoforms
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Biological Activity
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EGFR (WT) 1-10 nM (IC50) |
EGFR (L858R/T790M/C797S) <1 nM (IC50) |
EGFR-IN-30 (compound 27) inhibits A431 cell (IC50=100-1000 nM),Ba/F3_L858R/T790M/C797S cell (IC50<10 nM), Ba/F3_Del19/T790M/C797S cell (IC50<10 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2726463-68-7
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Molecular Weight 610.49
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Formula C28H33BrN7O2P
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SMILES
O=P(C)(C)C1=C(NC2=NC(NC3=C(OC)C=C4N(C(C)C)CCC5=C(C=NN5C)C4=C3)=NC=C2Br)C=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR-IN-30 Related Classifications
HY-144044 Related Classifications
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