1. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
  2. EGFR
  3. EGFR-IN-30

EGFR-IN-30 

Cat. No.: HY-144044
Handling Instructions

EGFR-IN-30 is a potent EGFR inhibitor with IC50s of 1-10 nM, <1 nM for EGFR (WT), EGFR (L858R/T790M/C797S), respectively. EGFR-IN-30 has potential for cell proliferative diseases, such as cancer research.

For research use only. We do not sell to patients.

EGFR-IN-30 Chemical Structure

EGFR-IN-30 Chemical Structure

CAS No. : 2726463-68-7

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Description

EGFR-IN-30 is a potent EGFR inhibitor with IC50s of 1-10 nM, <1 nM for EGFR (WT), EGFR (L858R/T790M/C797S), respectively. EGFR-IN-30 has potential for cell proliferative diseases, such as cancer research[1].

IC50 & Target[1]

EGFR (WT)

1-10 nM (IC50)

EGFR (L858R/T790M/C797S)

<1 nM (IC50)

In Vitro

EGFR-IN-30 (compound 27) inhibits A431 cell (IC50=100-1000 nM),Ba/F3_L858R/T790M/C797S cell (IC50<10 nM), Ba/F3_Del19/T790M/C797S cell (IC50<10 nM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

610.49

Formula

C28H33BrN7O2P

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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EGFR-IN-30
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HY-144044
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