EGFR-TK-IN-1
EGFR-TK-IN-1 (compound 7o) is a potent mutant EGFR inhibitor with IC50 of 8.5 nM an 9.3 nM against EGFRL858R/T790M and EGFRDel19.EGFR-TK-IN-1 showes strong antiproliferative effects against EGFR mutant-driven non-small cell lung cancer (NSCLC) cells and induces cell apoptosis.
For research use only. We do not sell to patients.
- Formula: C36H39N7O3
- Molecular Weight:617.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 617.74
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Formula C36H39N7O3
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SMILES
C=CC(NC1=CC=CC(N2C(COC3=CC=CC(OC)=C3)=CC4=CN=C(NC5=CC=C(N6CCC(N(C)C)CC6)C=C5)N=C42)=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)