Eleocharin B
Eleocharin B is a prenylated flavanone antioxidant and DPPH free radical scavenger. Eleocharin B is obtained from the peel of Eleocharis tuberosa (water chestnut). Eleocharin B is used in the study of oxidative stress-related disorders.
For research use only. We do not sell to patients.
- CAS No.: 1619976-97-4
- Formula: C20H18O6
- Molecular Weight:354.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Eleocharin B (0.1 mg/mL; 20 min) demonstrates significant reducing power in a cell-free ferricyanide reduction assay at 0.1 mg/mL, exceeding the reducing activity of Rutin (HY-N0148)[1].
Eleocharin B (0.05-16 mg/mL; 30 min) exerts strong DPPH radical scavenging activity in a cell-free assay, with potency exceeding that of rutin[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1619976-97-4
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Molecular Weight 354.35
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Formula C20H18O6
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SMILES
OC1=C2C(O[C@H](C3=CC(O)=C(C=C3)O)CC2=O)=CC4=C1C=CC(C)(O4)C
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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ROS/oxidative-stress fluorescent staining
ROS/oxidative-stress fluorescent staining uses cell-permeant fluorogenic probes that become fluorescent after oxidation inside cells or tissues; commonly used examples include DCFH-DA/DCFDA for broad cellular oxidant detection, DHE for superoxide-related signal detection, MitoSOX for mitochondrial superoxide-related signal detection, and CellROX probes for oxidative-stress-associated fluorescence readouts. The assay detects probe oxidation rather than a single ROS species unless the probe and analysis method have been chemically validated for that species. DCFH-DA enters cells, is deacetylated by intracellular esterases to DCFH, and produces fluorescent DCF after oxidation, so the readout is used as an operational measure of total cellular oxidative stress rather than a species-specific ROS measurement. DHE and MitoSOX can report superoxide-related oxidation, but red fluorescence alone can include non-specific ethidium-like oxidation products; HPLC or optimized spectral approaches are
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Eleocharin B Related Classifications
HY-N21601 Related Classifications
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