(+/-)-Epicatechin
(+/-)-Epicatechin is a xanthine oxidase inhibitor with an IC50 of 982.14 μM, and can be found in Semen Plantaginis (Plantago seed). (+/-)-Epicatechin can be used in research on diseases such as hyperuricemia and gout .
For research use only. We do not sell to patients.
- CAS No.: 13392-26-2
- Formula: C15H14O6
- Molecular Weight:290.27
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BALB/3T3 | IC50 |
>344 μM
Compound: 8
|
Growth inhibition of BALB/c mouse cloned 3T3/A31 cells after 72 hrs by nigrosin assay
Growth inhibition of BALB/c mouse cloned 3T3/A31 cells after 72 hrs by nigrosin assay
|
[PMID: 10096863] |
| Vero C1008 | IC50 |
>2.0 × 105M
Compound: COVC-1751771244
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
|
10.6019/CHEMBL4651402 |
Chemical Information
-
CAS No. 13392-26-2
-
Molecular Weight 290.27
-
Formula C15H14O6
-
SMILES
C1=CC(=C(C=C1C2C(CC3=C(C=C(C=C3O2)O)O)O)O)O
-
Synonyms
(+/-)-Epicatechol; (+/-)-epi-Catechin
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)