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Cat. No.: HY-130800R

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Eragidomide (Standard)

Name: Eragidomide (Standard)
Brand: MedChemExpress
SKU: HY-130800R
Availability: PreOrder

(Synonyms: CC-90009 (Standard))

Eragidomide (Standard) is the analytical standard of Eragidomide (HY-130800). This product is intended for research and analytical applications. Eragidomide (CC-90009) is a first-in-class GSPT1-selective cereblon (CRBN) E3 ligase modulator, acts as a molecular glue. Eragidomide coopts the CRL4^CRBN to selectively target GSPT1 for ubiquitination and proteasomal degradation.

For research use only. We do not sell to patients.

CAS No.: 1860875-51-9
Formula: C₂₂H₁₈ClF₂N₃O₄
Molecular Weight:461.85

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Eragidomide (Standard) Chemical Structure

CAS No.: 1860875-51-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1860875-51-9
Molecular Weight 461.85
Formula C₂₂H₁₈ClF₂N₃O₄
SMILES

O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)C(F)(F)C4=CC=C(Cl)C=C4
Synonyms

CC-90009 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Christine Surka, et al. CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells. Blood. 2021 Feb 4;137(5):661-677. [Content Brief]

[2]. Joshua D Hansen, et al. CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia. J Med Chem. 2021 Feb 25;64(4):1835-1843. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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