JC-10
Based on 1 Customer Validation
JC-10 is a lipophilic mitochondrial membrane potential indicator and is a fluorescent dye. JC-10 accumulates and aggregates in healthy mitochondria to emit red fluorescence; exists as a monomer emitting green fluorescence in the cytosol or apoptotic cells with collapsed mitochondrial membrane potential, enabling measurement of mitochondrial depolarization via the green/red fluorescence ratio.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.03%
- No. CAS: 5563-28-0
- Fòrmula: C25H29Cl2IN4
- Peso molecular:583.34
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Almacenamiento:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Actividad biológica
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Chemical Information
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- Pureza y Documentación
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Help & FAQs
Actividad biológica
Descripciòn
In Vitro
JC-10 (30 μM; 20 min) enables quantitative measurement of mitochondrial membrane potential collapse in human primary cortical neurons via changes in the green/red fluorescence ratio[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
- Mitochondrial membrane-potential fluorescent assay
- Detection of Apoptosis
- TUNEL staining for apoptotic DNA fragmentation
- Annexin V plus membrane-impermeant dye apoptosis staining
- Fluorescent plasma-membrane potential dye assay
- Mitochondrial membrane-potential and mitochondrial mass staining
- Apoptosis Solutions
Chemical Information
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No. CAS 5563-28-0
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Appearance Solid
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Peso molecular 583.34
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Fòrmula C25H29Cl2IN4
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Color Purple to purplish red
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SMILES
ClC1=CC=C2C(N(CC)/C(N2CC)=C/C=C/C3=[N+](CC)C4=C(C=C(C=C4)Cl)N3CC)=C1.[I-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JC-10 Related Classifications
HY-167255 Related Classifications
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