Lergotrile
Lergotrile is a potent and orally active dopamine agonist and a prolactin secretion inhibitor. Lergotrile inhibits prolactin release from pituitaries by activating an adenohypophyseal dopamine receptor. Lergotrile has the potential for the research of Parkinson's disease.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 36945-03-6
- Fòrmula: C17H18ClN3
- Peso molecular:299.80
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas Dopamine Receptor
More
Actividad biológica
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Sympathetic neuron | ED50 |
0.27 μM/kg
Compound: 2
|
Compound tested in vivo for sympathetic neuronal activity in cat cardioaccelerator nerve after iv administration
Compound tested in vivo for sympathetic neuronal activity in cat cardioaccelerator nerve after iv administration
|
[PMID: 6699883] |
| Sympathetic neuron | ED50 |
0.27 μmol/Kg
Compound: 2
|
Compound tested in vivo for sympathetic neuronal activity in cat cardioaccelerator nerve after iv administration
Compound tested in vivo for sympathetic neuronal activity in cat cardioaccelerator nerve after iv administration
|
[PMID: 6699883] |
Chemical Information
-
No. CAS 36945-03-6
-
Peso molecular 299.80
-
Fòrmula C17H18ClN3
-
SMILES
ClC1=C2C3=C(N1)C=CC=C3[C@]4([H])[C@@](N(C[C@@H](C4)CC#N)C)([H])C2
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Clemens JA, et al. Inhibition of prolactin secretion by lergotrile mesylate: mechanism of action. Acta Endocrinol (Copenh). 1975 Jun;79(2):230-7. [Content Brief]
[2]. Lemberger L, et al. The inhibitory effect of an ergoline derivative (lergotrile, compound 83636) on prolactin secretion in man. J Clin Endocrinol Metab. 1974 Sep;39(3):579-84. [Content Brief]
[3]. Lieberman A, et al. Treatment of Parkinson's disease with lergotrile mesylate. JAMA. 1977 Nov 28;238(22):2380-2. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lergotrile Related Classifications
HY-107002 Related Classifications
Powered by Bioz