PPI-4955
PPI-4955 is a subtype 1 (S1P₁) agonist of sphingosine-1-phosphate receptor with an EC50 of 1.62 nM. PPI-4955-P (the active phosphorylated form) exhibits excellent receptor selectivity and affinity, and the IC50 values for hS1P₁, hS1P₃, hS1P₄, and hS1P₅ are 0.23, 2000, 6.5, and 184 nM respectively. PPI-4955 has significantly improved in vivo phosphorylation efficiency, which can reduce lymphocytes and improve cardiovascular risk. PPI-4955 can be used in immunomodulation research.
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- No. CAS: 911412-31-2
- Fòrmula: C26H24F3N3O2
- Peso molecular:467.48
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 911412-31-2
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Peso molecular 467.48
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Fòrmula C26H24F3N3O2
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SMILES
C[C@@](CO)(N)C1=NC=C(N1)C2=CC(C(F)(F)F)=C(OCC3=CC=C(C4=CC=CC=C4)C=C3)C=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PPI-4955 Related Classifications
HY-16621 Related Classifications
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