PSB-18422
PSB-18422 is a GPR17 agonist, with an EC50 of 0.0279 μM for humans, 0.47 μM for rats, 0.753 μM for mice, and a human Ki of 1.46 μM. PSB-18422 triggers intracellular calcium mobilization via cross-species activation of GPR17. PSB-18422 can be used in the research of allergic bronchial inflammation.
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- No. CAS: 2244978-64-9
- Fòrmula: C12H9BrFNO4
- Peso molecular:330.11
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
PSB-18422 (Compound 33) potently activates human GPR17 in 1321N1 astrocytoma cells, with an EC50 of 0.0279 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2244978-64-9
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Peso molecular 330.11
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Fòrmula C12H9BrFNO4
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SMILES
O=C(C1=C(CCC(O)=O)C2=C(C=C(C=C2F)Br)N1)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PSB-18422 Related Classifications
HY-182724 Related Classifications
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