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Fanastomig

(Synonyms: EMB-02)
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Based on 1 Customer Validation

Fanastomig (EMB-02) is a bispecific antibody against PD-1/LAG3. Fanastomig exhibits potential immune checkpoint inhibitory activity and antineoplastic activity.

For research use only. We do not sell to patients.

  • Purity: 95.478%
  • CAS No.: 2761795-00-8
  • Molecular Weight:191.337 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Fanastomig
  • Experimental Validation Results for Fanastomig
  • Experimental Validation Results for Fanastomig
  • Experimental Validation Results for Fanastomig
  • Experimental Validation Results for Fanastomig
  • Fanastomig Chemical Structure
    Fanastomig Chemical Structure
CAS No.: 2761795-00-8
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    VK-CK-VH-CH1-h-CH2-CH3_L-kappa_Fab-G1-kappa

  • 1/16

    Immobilized PD-1 Protein, Human (147a.a, HEK293, His, HY-P70766) can bind Fanastomig. The EC50 for this effect is 3.686 ng/mL.

  • 1/16

    Immobilized LAG-3 Protein, Human (HEK293, His, HY-P70722) can bind Fanastomig. The EC50 for this effect is 4.675 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Juakat cells with Fanastomig (HY-P990740, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Flow Cytometry analysis of Raji cells labelling LAG3 (red) with Fanastomig (anti-LAG3) (HY-P990740). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Fanastomig Chemical Structure
    1/16
  • Fanastomig
  • Immobilized PD-1 Protein, Human (147a.a, HEK293, His, HY-P70766) can bind Fanastomig. The EC50 for this effect is 3.686 ng/mL.
  • Immobilized LAG-3 Protein, Human (HEK293, His, HY-P70722) can bind Fanastomig. The EC50 for this effect is 4.675 ng/mL.
  • Flow cytometric analysis of 1X106 Juakat cells with Fanastomig (HY-P990740, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Flow Cytometry analysis of Raji cells labelling LAG3 (red) with Fanastomig (anti-LAG3) (HY-P990740). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • VK-CK-VH-CH1-h-CH2-CH3_L-kappa_Fab-G1-kappa