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Cat. No.: HY-114830

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Fenleuton

Fenleuton is a 5-lipoxygenase inhibitor. Fenleuton is promising for research of leukotriene-mediated inflammatory diseases.

For research use only. We do not sell to patients.

CAS No.: 141579-54-6
Formula: C₁₇H₁₅FN₂O₃
Molecular Weight:314.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Fenleuton Chemical Structure

CAS No.: 141579-54-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Fenleuton is a 5-lipoxygenase inhibitor. Fenleuton is promising for research of leukotriene-mediated inflammatory diseases^[1].

All Lipoxygenase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
RBL-1	IC₅₀	0.3 μM Compound: 15c	Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE production Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE production	[PMID: 9207936]

Chemical Information

CAS No. 141579-54-6
Molecular Weight 314.31
Formula C₁₇H₁₅FN₂O₃
SMILES

O=C(N)N(C(C)C#CC1=CC=CC(OC2=CC=C(F)C=C2)=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Thomas A V, et al. Fenleuton: Development of a Manufacturing Process[J]. Organic Process Research & Development, 1997, 1(4): 294-299.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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Fenleuton

All Lipoxygenase Isoforms