Finerenone (Standard)
Based on 1 Customer Validation
Finerenone (Standard) is the analytical standard of Finerenone. This product is intended for research and analytical applications. Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.59%
- CAS. Nr.: 1050477-31-0
- Formel: C21H22N4O3
- Molecular Weight:378.42
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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HY-111372
FinerenoneMineralocorticoid Receptor Antagonist -
HY-B0251
EplerenoneAldosterone Blocker -
HY-B0251R
Eplerenone (Standard) -
HY-100471
EsaxerenoneMineralocorticoid Antagonist -
HY-113447
11-DehydrocorticosteroneEndogenous Corticosteroid -
HY-132809
BaxdrostatAldosterone Synthase Inhibitor -
HY-16276
OsilodrostatCYP11B1/CYP11B2 Inhibitor -
HY-109002
ApararenoneMineralocorticoid Receptor Antagonist -
HY-B1203A
Fludrocortisone acetateMineralocorticoid -
HY-B1203AR
Fludrocortisone acetate (Standard) -
HY-100471R
Esaxerenone (Standard)Mineralocorticoid Antagonist -
HY-109002R
Apararenone (Standard)Reference Standard
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 1050477-31-0
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Appearance Solid
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Molecular Weight 378.42
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Formel C21H22N4O3
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Color White to off-white
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SMILES
O=C(C1=C(C)NC2=C(C(OCC)=NC=C2C)[C@@H]1C3=CC=C(C#N)C=C3OC)N
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Synonyms
BAY 94-8862 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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SDS (788 KB)
- English - EN (788 KB)
- Français - FR (788 KB)
- Deutsch - DE (788 KB)
- Norwegian - NO (788 KB)
- Español - ES (788 KB)
- Swedish - SV (788 KB)
- Italian - IT (788 KB)
- Korean - KR (788 KB)
- Portuguese - PT (788 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Bärfacker L, et al. Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases. ChemMedChem. 2012;7(8):1385-1403. [Content Brief]
[2]. González-Blázquez R, et al. Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress. Front Pharmacol. 2018;9:1131. Published 2018 Oct 9. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Finerenone (Standard) Related Classifications
HY-111372R Related Classifications
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