FLT3/VEGFR2-IN-1
FLT3/VEGFR2-IN-1 (Compound 26) is a FLT3/VEGFR2/HDAC inhibitor with IC50 values of 14.5 nM, 3.9 nM, and 30.8 nM for FLT3, VEGFR2, and HDAC1, respectively. FLT3/VEGFR2-IN-1 can inhibit the phosphorylation of STAT3 and ERK1/2 and the proliferation of leukemia cells. FLT3/VEGFR2-IN-1 has anti-tumor activity and can be used for the research of acute myeloid leukemia.
For research use only. We do not sell to patients.
- Formula: C29H35N7O5
- Molecular Weight:561.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Biological Activity
Chemical Information
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Molecular Weight 561.63
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Formula C29H35N7O5
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SMILES
O=C(NC1=CC=C(C=C1)OC2=CC=NC(C3=CN(N=C3)CCCCCCC(NO)=O)=C2)NC4=NOC(C(C)(C)C)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FLT3/VEGFR2-IN-1 Related Classifications
HY-168493 Related Classifications
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