2. Protein Tyrosine Kinase/RTK
  3. c-Met/HGFR
  4. Fosgonimeton

Fosgonimeton  (Synonyms: ATH-1017)

Cat. No.: HY-132814 Purity: 99.61%
COA Handling Instructions

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Fosgonimeton (ATH-1017) is a hepatocyte growth factor receptor agonist (WO2017210489).

For research use only. We do not sell to patients.

Fosgonimeton Chemical Structure

Fosgonimeton Chemical Structure

CAS No. : 2093305-05-4

Size Price Stock Quantity
5 mg USD 260 In-stock
10 mg USD 380 In-stock
25 mg USD 800 In-stock
50 mg USD 1280 In-stock
100 mg USD 2100 In-stock
200 mg   Get quote  
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Fosgonimeton Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Fosgonimeton (ATH-1017) is a hepatocyte growth factor receptor agonist (WO2017210489)[1].

IC50 & Target

HGF Receptor[1]
In Vitro

Fosgonimeton is a hepatocyte growth factor receptor agonist[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fosgonimeton Related Antibodies
In Vivo

肝细胞生长因子受体激动剂

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

584.64

Formula

C27H45N4O8P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(O)(O)OC(C=C1)=CC=C1C[C@H](NC(CCCCC)=O)C(N[C@@H]([C@@H](C)CC)C(NCCCCCC(N)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (213.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7105 mL 8.5523 mL 17.1045 mL
5 mM 0.3421 mL 1.7105 mL 3.4209 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7105 mL 8.5523 mL 17.1045 mL 42.7614 mL
5 mM 0.3421 mL 1.7105 mL 3.4209 mL 8.5523 mL
10 mM 0.1710 mL 0.8552 mL 1.7105 mL 4.2761 mL
15 mM 0.1140 mL 0.5702 mL 1.1403 mL 2.8508 mL
20 mM 0.0855 mL 0.4276 mL 0.8552 mL 2.1381 mL
25 mM 0.0684 mL 0.3421 mL 0.6842 mL 1.7105 mL
30 mM 0.0570 mL 0.2851 mL 0.5702 mL 1.4254 mL
40 mM 0.0428 mL 0.2138 mL 0.4276 mL 1.0690 mL
50 mM 0.0342 mL 0.1710 mL 0.3421 mL 0.8552 mL
60 mM 0.0285 mL 0.1425 mL 0.2851 mL 0.7127 mL
80 mM 0.0214 mL 0.1069 mL 0.2138 mL 0.5345 mL
100 mM 0.0171 mL 0.0855 mL 0.1710 mL 0.4276 mL
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Fosgonimeton Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fosgonimeton2093305-05-4ATH-1017ATH1017ATH 1017c-Met/HGFRInhibitorinhibitorinhibit

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