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Cat. No.: HY-123247

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LY113174

LY113174 is an orally active aromatase inhibitor (IC₅₀ = 24 nM). LY113174 blocks testosterone induced increase in uterine weight in rat, and inhibits ovarian estrogen biosynthesis.

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CAS No.: 112959-07-6
Formule: C₁₇H₁₀Cl₂N₂
Masse moléculaire:313.18

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

LY113174 Chemical Structure

CAS No.: 112959-07-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

LY113174 is an orally active aromatase inhibitor (IC₅₀ = 24 nM). LY113174 blocks testosterone induced increase in uterine weight in rat, and inhibits ovarian estrogen biosynthesis^[1].

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Chemical Information

CAS No. 112959-07-6
Masse moléculaire 313.18
Formule C₁₇H₁₀Cl₂N₂
SMILES

ClC1=CC=C(C=C1)C2C3=C(C=C(C=C3)Cl)C4=NC=NC=C42
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hirsch KS, et al. Discovery and development of a novel class of nonsteroidal aromatase inhibitors. Steroids. 1987 Jul-Sep;50(1-3):201-17. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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LY113174

Voir tous les produits spécifiques à Isoform Cytochrome P450

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

LY113174 Related Classifications

HY-123247 Related Classifications