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Cat. No.: HY-N10204

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Rostratin B

Rostratin B, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC₅₀ of 1.9 μg/mL.

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CAS No.: 752236-17-2
Formule: C₁₈H₂₀N₂O₆S₂
Masse moléculaire:424.49

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Rostratin B Chemical Structure

CAS No.: 752236-17-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

Rostratin B, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC₅₀ of 1.9 μg/mL^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	4.4 μM Compound: 2	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 15332857]

Chemical Information

CAS No. 752236-17-2
Masse moléculaire 424.49
Formule C₁₈H₂₀N₂O₆S₂
SMILES

O=C(N1[C@]([C@H](CC2)O)([H])[C@](C2=O)([H])C3)[C@@]4(SS[C@]13C5=O)N5[C@]([C@H](CC6)O)([H])[C@](C6=O)([H])C4
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
- Microorganisms
Exserohilum rostratum
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Tan RX, et al. Isolation and structure assignments of rostratins A-D, cytotoxic disulfides produced by the marine-derived fungus Exserohilum rostratum. J Nat Prod. 2004;67(8):1374-1382. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Rostratin B

Voir tous les produits spécifiques à Isoform Endogenous Metabolite

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Rostratin B Related Classifications

HY-N10204 Related Classifications