1. Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
    Membrane Transporter/Ion Channel
    Apoptosis
  2. Reactive Oxygen Species
    P-glycoprotein
    Apoptosis
  3. Furanodiene

Furanodiene 

Cat. No.: HY-126940
Handling Instructions

Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level.

For research use only. We do not sell to patients.

Furanodiene Chemical Structure

Furanodiene Chemical Structure

CAS No. : 19912-61-9

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Description

Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level[1].

In Vitro

Furanodiene (1.4, 4.1, 12.2 uM; 48 hours) is effective in treating human JF 305 pancreatic cancer cells and MCF-7 breast cancer cells xenotranplanted into the zebrafish[1].
Furanodiene has no effect on Pgp related gene (MDR1) expression[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

216.32

Formula

C₁₅H₂₀O

CAS No.
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Please store the product under the recommended conditions in the Certificate of Analysis.

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Furanodiene
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