Ganoderic acid R

Cat. No.: HY-N11638: FAQs
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Ganoderic acid R is a potent anticancer agent. Ganoderic acid R inhibits the growth by inducing apoptosis on tumor cell line. Ganoderic acid R possesses significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1).

For research use only. We do not sell to patients.

Ganoderic acid R Chemical Structure

CAS No. : 103963-39-9

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Description

In Vitro

Ganoderic acid R (0-50 µg/mL, 48 h) inhibit the growth by inducing apoptosis on tumor cell lines at the concentrations that more than 20 µg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis^[1]

Cell Line:	KB-A-1/Dox cells
Concentration:	0, 25, 50 μg/mL
Incubation Time:	48 h
Result:	Induced the cellular apoptosis, the number of apoptotic cells was increased from 35% to 90% during 48 h.

Molecular Weight

554.76

Formula

C₃₄H₅₀O₆

CAS No.

103963-39-9

SMILES

C[C@@]12C3=CC[C@](C)([C@@](CC4)([H])[C@H](C)[C@@H](OC(C)=O)C/C=C(C)/C(O)=O)[C@]4(C)C3=CC[C@@]1([H])C(C)([C@@H](CC2)OC(C)=O)C

Structure Classification

Initial Source

Microorganisms

glossy ganoderma

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ouyang J J, et al. Ganoderic Acid Restores the Sensitivity of Multidrug Resistance Cancer Cells to Doxorubicin. Advanced Materials Research, 2014, 834-836:573-576.

Ganoderic acid R Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganoderic acid R103963-39-9ApoptosisAnticancerKB-A-1/Dox cellsKB-A-1 cellsGanoderic acidInhibitorinhibitorinhibit

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